Skip to main content
Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Self-immolative nanocapsules precisely regulate depressive neuronal microenvironment for synergistic antidepression therapy

Fig. 7

Differentially expressed genes (DEGs) profiles in Sham, CUMS + Saline, and CUMS + VCNCs. A Volcano plot comparing Sham vs CUMS + Saline cases. Upregulated genes (n = 143) are represented in red, while downregulated genes (n = 47) are represented in green. B The top 20 KEGG pathways for DEGs in the Sham vs CUMS + Saline group. C Volcano plot comparing CUMS + VCNCs vs CUMS + Saline cases. Upregulated genes (n = 325) are represented in red, while downregulated genes (n = 115) are represented in green. D The top 20 KEGG pathways for DEGs in the CUMS + VCNCs vs CUMS + Saline group. E The most significant GO terms associated with DEGs in Sham vs CUMS + Saline and F CUMS + VCNCs vs CUMS + Saline groups. The DEGs and significant pathways are identified using the criteria of | log2(FC)|≥ 1.5 and padj < 0.05. G GSEA analysis of GO terms applied to the Sham vs CUMS + Saline and CUMS + VCNCs vs CUMS + Saline groups. The results are from three independent samples (n = 3)

Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us