Fig. 1
Characterization of ILA@Lip. a UV–vis–NIR absorption spectrum of lenvatinib, AQ4N, IR 780, ILA@Lip. b TEM image of ILA@Lip in water solution. Scale bar = 100 nm. c TEM image of an enlarged detail of ILA@Lip. d. The particle size distribution of ILA@Lip. Mean only, n = 3. e Relative particle size distribution of ILA@Lip in PBS of different pH. f Relative particle size distribution changes of ILA@Lip after the store for 0 days, 7 days, and 14 days. Mean only, n = 3. g The surface zeta potential of ILA@Lip after the store for 0 days, 7 days, and 14 days. Mean ± S.D., n = 3. h Absorbance decay curves of free IR 780, and ILA@Lip at 780 nm after the radiation of 808 nm laser (1.0 W cm−2) for a period of time. Results are presented as percentages by normalizing to absorbance intensity obtained before laser irradiation. Mean only, n = 3. i The corresponding photographs of ILA@Lip were stored in PBS, FBS, RPMI 1640, and DMEM for 0 days, 7 days, and 14 days