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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Targeting macrophage M1 polarization suppression through PCAF inhibition alleviates autoimmune arthritis via synergistic NF-κB and H3K9Ac blockade

Fig. 6

DSNPs could be selectively absorbed by activated macrophages. (a, b) Size distributions of DSNPs and garcinol-DSNPs in distilled water at 25 ℃ and TEM images are shown. (c) Zeta potential values of the DSNPs and garcinol-DSNPs. (d) Profile showing in vitro release of garcinol from DSNPs in PBS. (e) Curve showing the change in garcinol-DSNP size over 5 days. (f) The stability of garcinol-DSNPs in serum was determined by DLS. (g) In vitro cellular uptake of DSNPs by RAW264.7 cells (LPS±) and human-derived macrophages (LPS±/IFN-γ±). (h) Summary of the physicochemical characteristics of garcinol-DSNPs and DSNPs

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Journal of Nanobiotechnology

ISSN: 1477-3155

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