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Table 2 Comparison of clinical characteristics and OCT findings between the CSC responders and CSC non-responders

From: Exosomal miR-184 in the aqueous humor of patients with central serous chorioretinopathy: a potential diagnostic and prognostic biomarker

 

CSC Responders (n = 17, 40.5%)

CSC non-responders (n = 25, 59.5%)

p-value

Clinical characteristics

 Sex (male: female)

14: 3

20: 5

 

 Age (years)

51.1 ± 7.5

50.5 ± 9.4

0.965†

 Hypertension (yes: no)

4: 13

3: 22

0.325*

 Diabetes (yes: no)

0: 17

0: 25

1.000*

 Visual acuity (LogMAR)

0.251 ± 0.317

0.211 ± 0.269

0.662†

 Duration of symptom (wk)

10.5 ± 4.8

8.6 ± 3.9

0.162†

 First event: Recurrence

14: 3

21:4

0.888*

Baseline OCT findings

 Baseline CRT (µm)

424.65 ± 129.56

458.52 ± 122.41

0.395†

 Baseline SFChT (µm)

379.86 ± 118.08

366.82 ± 96.58

0.697†

 Baseline SRF height (µm)

256.25 ± 164.81

225.94 ± 126.07

0.504†

 Baseline PED height (µm)

63.18 ± 38.18

61.51 ± 96.04

0.938†

Changes of OCT findings at 1 month after bevacizumab

 Δ CRT (µm)

− 198.73 ± 122.32

− 88.00 ± 125.43

0.010†

 Δ SFChT (µm)

− 63.92 ± 51.81

− 23.00 ± 33.24

0.005†

 Δ SRF height (µm)

− 259.73 ± 138.00

− 67.18 ± 121.72

 < 0.001†

 Δ PED height (µm)

− 28.94 ± 41.48

− 11.69 ± 30.88

0.146†

  1. *Chi-square test, †Unpaired t-test
  2. CSC central serous chorioretinopathy, CRT central retinal thickness, LogMAR Logarithm of the Minimum Angle of Resolution, SFChT subfoveal choroidal thickness, SRF subretinal fluid, PED pigment epithelial detachment