Fig. 1
From: Advances in nanomedicines for lymphatic imaging and therapy
A schematic represents the application of lymph node-specific nanomedicine (upper panel), design strategies (middle panel) and optimization strategies (below panel). Upper panel shows the schematic of the main application of lymph node-specific nanoparticles, including lymph node diagnosis and drug delivery and enhanced image recognition. And the mode of administration of subcutaneous injection, intravenous injection and intralymphatic injection. Middle panel illustrates the lymph node specific nanomedicine design strategies including vesicle detach, surface modification, responsive drug release, and NPs dissociate. Below panel illustrates the lymph node specific nanomedicine optimization strategies