Fig. 4
From: Advances in nanomedicines for lymphatic imaging and therapy
Copyright © 2022 National Academy of Sciences
Screening and optimization of lipid nanoparticles (LNPs) with targeting ability to lymph nodes (LNs). A The chemical structure of lipids used in this study. B The bioluminescence within inguinal LNs after treatment with LNP/mLuc. C The bioluminescence within inguinal LNs after treatment by LNP/mLuc. D Representative images of bioluminescence distribution in mice treated with 113-O12B/mLuc and ALC-0315/mLuc. E Ratio of radiance in liver and inguinal LNs after subcutaneous injection of mLuc [58].