Fig. 5

Photothermal therapy and anti-tumor evaluation of T-MP in metastatic sentinel lymph nodes in a mouse model of HER2 HT-29 colon cancer cells. A Illustration of the treatment of the surgical resection of orthotopic tumor and follow-up laser irradiation of the meta-static LNs. B Temperature increase of the metastatic LNs was recorded using Testo 890 thermal imager. C Representative TEM images of LN sections after photothermal therapy. D Representative bioluminescence imaging of the mice before tumor resection and after tumor resection and photothermal therapy. E Quantified bioluminescence intensity in panel D. F Survival of the mice with indicated treatments. G Mice body weight [69].