Fig. 7

Macroscopic observations and histological staining of Achilles tendons treated with different types of nanofibers at 3 weeks post-surgery. (A) Surgical procedure by which the nanofibrous membranes were wrapped around the Achilles tendon. (B) Macroscopic observations of tendons in each group. (C) H&E staining and Masson staining of the interface between the tendon and surrounding tissues. (D) Macroscopic assessments of adhesions. (E) Macroscopic shape assessments. (F) Histological assessments of adhesions. (G) Histological assessments of the inflammatory response. The data are presented as the mean ± standard deviation from four experimental replicates. Statistical analysis was performed by one-way ANOVA with Tukey’s post hoc analysis. *p < 0.05; **p < 0.01, ***p < 0.001; ns indicates no significance