Fig. 8

Evaluation of inflammatory responses elicited by the nanofibers at 3 weeks post-surgery. Immunofluorescence analysis of the inflammatory factors (A) IL-1b and (B) TNF-a in the implanted nanofibers. Fluorescence intensity analysis of (C) IL-1b and (D) TNF-α expression. (D) Conceptual graphs of the immune microenvironment of tendons. The data are presented as the mean ± standard deviation from four experimental replicates. Statistical analysis was performed by one-way ANOVA with Tukey’s post hoc analysis. *p < 0.05; **p < 0.01, ***p < 0.001; ns indicates no significance