Fig. 5
From: Effective treatment of metastatic sentinel lymph nodes by dual-targeting melittin nanoparticles
In vivo evaluations of the inhibition effect of MLT-HA-HPPS on the breast cancer growth. a Tumor volume curves of 4T1 tumors in each group with three times paracancer injection after 2 days of hock inoculation tfRFP-4T1 cells. Tumor volume in the MLT-HA-HPPS-treated group was significantly inhibited compared to the other groups. b In vivo mice photographs and c Ex vivo tumors from each group on the 14th day. d Quantitative analysis of tumor weight in different groups. 3–4 mice/group. e Changes in body weight of mice during treatment. Data are shown as the mean ± SD. ns means not significant. *P < 0.05, **P < 0.01, ***P < 0.001