Fig. 8
From: Mackinawite nanozymes as reactive oxygen species scavengers for acute kidney injury alleviation
Therapeutic mechanisms of GFeSNs on AKI. a Fluorescence images of TUNEL-stained kidney sections from each group. b H&E staining of kidney tissues from each group. c PCA was performed on DEGs from the kidneys of GFeSN- and PBS-treated AKI mice (n = 5). Each data point corresponds to PCA of each sample. d Venn diagram of transcriptomic profiles of PBS- and GFeSN-treated AKI mice. e Volcano plots showing up-regulated and down-regulated genes by GFeSNs. f GSEA was performed to analyze enriched signaling pathways. Top 20 most significantly enriched pathways are shown. g GSEA identified two representative signaling pathways regulated by GFeSN treatment