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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy

Fig. 1

Characterization and enzyme-like activity of NPs. (a, b) HRTEM images of CuS. NPs are highlighted with white dotted lines. (c) The lattice spacing of CuS NPs. (d) XRD pattern of the synthesized CuS NPs corresponds with the standard Cu1.95 S crystal phases. (e, f) XPS spectra of CuS NPs. (g) Peroxidase-like activities of CuS NPs at different time intervals (0, 5, 10, 15, and 30 min). Inset: (I) TMB + H2O2, (II) TMB + CuS NPs, and (III) TMB + H2O2 + CuS NPs. The solution of CuS NPs + H2O2 + TMB generates blue reaction products from the oxidation of TMB, indicating the peroxidase-like activity of CuS NPs. (h) Fluorescence spectra after the reaction of CuS, TA, and H2O2, demonstrating that CuS NPs catalyze ∙OH formation from H2O2. (i) Absorption spectra of B2M antibody, CuS, and B2M-CuS NPs.

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Journal of Nanobiotechnology

ISSN: 1477-3155

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