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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy

Fig. 2

Targeting of senescent cells by B2M-CuS NPs. (a) Representative fluorescent images of senescent chondrocytes co-cultured with FITC-labeled CuS or B2M-CuS NPs. Stronger green fluorescence (the FITC-labeled NPs) was observed in the B2M-CuS group relative to the CuS group. Nuclei were stained with DAPI (blue fluorescence). (b) Representative flow cytometry images of FITC fluorescence analysis in senescent cells co-cultured with NPs. (c) Quantitative analysis of the mean fluorescence intensity of FITC calculated from (b). Data are presented as mean ± SD (n = 3). *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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