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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy

Fig. 5

Chondro-inductivity of B2M-CuS NPs. (a-d) Relative mRNA expression of Acan and Col-2 in chondrocytes after co-culturing with NPs for 7 and 14 days. (e) GAG deposition (visualized by alcian blue staining; blue color) in chondrocytes after co-culturing with NPs for 7 days. (f) Immunohistochemistry staining of Col-2 (brown color) in cell pellets co-cultured with NPs for 21 days. Data are presented as mean ± SD (n = 3). *p<0.05, **p<0.01, ***p<0.001, and ****p<0.0001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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