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Scheme 1 | Journal of Nanobiotechnology

Scheme 1

From: Conversion of senescent cartilage into a pro-chondrogenic microenvironment with antibody-functionalized copper sulfate nanoparticles for efficient osteoarthritis therapy

Scheme 1

Schematic illustration of the application of B2M-CuS NPs in OA therapy. CuS NPs were functionalized with B2M antibody. The resultant B2M-CuS NPs have peroxidase-like activity and selectively target senescent chondrocytes for elimination while promoting chondrogenesis. Therefore, B2M-CuS NPs may be a low-toxicity solution for the generation of a pro-chondrogenic microenvironment that supports the remodeling and regeneration of senescent cartilage in OA.

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Journal of Nanobiotechnology

ISSN: 1477-3155

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