Fig. 6

A A schematic diagram of the experimental design. B A representative photomicrograph of the aorta with frontal ORO staining. C The quantification assessment regarding the lesion area (n = 5). D Cross-section of ORO-stained aortic root (Bar = 100 μm). E The quantification of the area of lipid deposition on cross sections in the aortic root (n = 5). F Cholesterol areas with Schultz method staining (Bar = 100 µm). G The area of cholesterol deposition on cross-sections of the aortic root was quantified (n = 5). (*p < 0.05, **p < 0.01, ***p < 0.001 and n.s., no significance)