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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Human milk extracellular vesicles enhance muscle growth and physical performance of immature mice associating with Akt/mTOR/p70s6k signaling pathway

Fig. 5

Combining HME with Rapamycin at the C2C12 level. (A): Rapamycin exerts an inhibitory effect on C2C12 cells in a dose-dependent manner, the cell survival rate of the control group was set to 100%. (B): Representative Jenner-Giemsa staining images of myotubes. (C-D): Myotubes densities calculated as the sum of pixels attributed to tones 0-150. (E-F): Effects of HME and BME on the length and diameter of C2C12 myotubes. (G-J): Protein levels of p-mTOR/mTOR, p-P70S6K/P70S6K, and p-4E-BP1/4E-BP1 in the C2C12 cells. Data are presented as mean ± SE, the * indicates p < 0.05

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