Fig. 4

Biodistribution of DID NE@SA in mice with or without DSS-induced IBD. A DID fluorescence imaging of the stomach and intestines at different time points after oral administration of DID NE@SA, and B semi-quantitative analysis of the fluorescence intensity. Data are shown as mean ± SD (n = 3). *p < 0.05, **p < 0.01. In vitro imaging of DID fluorescence in C heart, liver, spleen, lung, kidney and D small intestine and colon 24 h after administration