Fig. 5

Evaluation of the in vivo treatment efficacy. A Schematic representation of the experimental procedure of IBD induction and oral gavage preparations in mice. B Weight change after different treatments and C disease index score. D Representative photographs of the colon from the different treatment groups. E Quantification of colon length, unit (cm), F colon weight divided by colon length, unit (g/cm), G weight divided by weight, unit (g/g), H kidney weight divided by weight, unit (g/g). Data are shown as mean ± SD (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. I HE staining of the colon in the different treatment groups. Scale bar were 100 μm