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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Injectable photocrosslinking spherical hydrogel-encapsulated targeting peptide-modified engineered exosomes for osteoarthritis therapy

Fig. 6

W-Exo-L@GelMA inhibits osteophyte formation and subchondral bone loss in the OA murine model. A Micro-CT representative images of the bone surface and the coronal plane of the subchondral bone of joints. W-Exo-L@GelMA notably reduced the osteophyte formation of the surface and the loss of subchondral bone. B Quantitative analysis of the parameters of tibial subchondral bone: trabecular number (Tb. N), volume/tissue volume (BV/TV), trabecular thickness (Tb. Th), and trabecular separation (Tb. Sp). Data represent mean ± SD; N = 6/group. *P < 0.05; **P < 0.01 by one-way ANOVA

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