Fig. 4
From: Dendrimer-conjugated isotretinoin for controlled transdermal drug delivery
Controlled release properties of 13cRA-D. A Controlled release of isotretinoin from 13cRA-D at pH 5.0 and pH 7.0 in a hydroalcoholic solution over 48 h. B Penetration of 13cRA and 13cRA-D through the pig dermis, monitored over 10 h. Data are presented as the mean ± standard deviation (SD), n = 3. 13cRA-D dendrimer-conjugated isotretinoin