Fig. 6
From: Dendrimer-conjugated isotretinoin for controlled transdermal drug delivery
13cRA-D induces less skin irritation than free 13cRA. Representative images of the skin after application of phosphate-buffered saline (PBS) (A), Dendrimer(B),13cRA (C), or 13cRA-D (D) for 6 h at an approximate dose of 0.5 g. E Skin irritation scores. Data are presented as mean ± standard deviation (SD) (n = 3). 13cRA-D dendrimer-conjugated isotretinoin