Fig. 5

Antitumor performance of S-GDY in vivo. A Time-dependent tumor volume curves after different treatments (n = 5), B Tumor weight curves after different treatments (n = 5), C Photographs of tumors dissected from mice in four groups after various treatments (n = 5), D H&E and TUNEL staining of tumor regions after different treatments (scale bar: 20 µm), E Concentration of GSH in tumors (n = 5). F Western blot analysis on the expressions of GPX4 and Cleaved-Caspase-3 in tumors. G Survival time of 4T1 tumor-bearing mice (n = 5)