Fig. 3
From: Biomimetic nanovesicle co-delivery system impairs energy metabolism for cancer treatment
The cytotoxicity and mechanism of action studies. A Cytotoxicity of different concentrations of Met towards 4T1 cells. B Cytotoxicity of different concentrations of 3BP towards 4T1 cells. C Combined index (CI) of different concentration ratios of Met and3BP. D Cytotoxicity of different drug formulations towards 4T1 cells. E The effects of the drug formulations on glucose consumption. F The effects of the drug formulations on lactate generation. G Flow cytometry analysis histogram of cell cycle distribution after treatment. H Quantitative analysis of cell cycle phase distributions for each group. I Flow cytometry analysis of apoptosis after treatment. J Percentage of apoptotic and necrotic cell populations in the treated 4T1 cells. The experimental results represent the mean ± SD