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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Application of biomedical materials in the diagnosis and treatment of myocardial infarction

Fig. 3

UCCy@Gel functions in MI mice. (A) Schematic illustration for the synthesis of UCCy@Gel (I), the schematic illustration for the structure of cyanobacteria (II). (B) SEM and TEM images of UCCy@Gel. (C) Schematic diagram of photosynthesis and respiration of UCCy@Gel. (D) (I) UCCy@Gel + 980 nm NIR light irradiation, (II) UCCy@Gel + white light irradiation, (III) Cyanobacteria + 980 nm NIR light irradiation, (IV) PBS + 980 nm NIR light irradiation and (V) time-oxygen release curves of UCCy@Gel in the dark. (E) Activity of UCCy@Gel (green = NIR on; white = dark treatment). (F) Schematic representation of dark hypoxia-preconditioned mice and echocardiographic examination of mouse hearts 6 h after modeling and (G) assessment of cardiac function by echocardiography. (H) Fluorescence staining of HSP70 protein in heat shock after dark hypoxia pretreatment. (I) Immunofluorescent staining of CD206 and (J) Western blot and quantification of iNOS (M1 macrophage marker) in mouse heart after 980 nm NIR treatment of MI mice for 72 h. Reproduced under terms of the CC-BY license [159]. Copyright 2022, Liu Y, published by Wiley-VCH.

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