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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Autophagy-amplifying nanoparticles evoke immunogenic cell death combined with anti-PD-1/PD-L1 for residual tumors immunotherapy after RFA

Fig. 8

SBZP inhibits the growth of residual tumors after IRFA. A Flow chart of in vivo IRFA for subcutaneous tumors with the treatment of NPs. B Immunoblotting of LC3B in tumor tissues treated with different NPs. C, E IVIS bioluminescent imaging and quantitative analysis of mice tumors before and 24 days after IRFA (n = 5). D, F, H, I Photos, weights, and volumes of the tumors in mice were treated with different NPs (n = 5). G Representative CLSM graphs of TUNEL, Ki-67 fluorescent staining, and H&E of tumor tissues treated with different NPs. Scale: 100 µm. Results were expressed as mean ± SD, *pp < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. IVIS, In vivo Imaging System

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