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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: An injectable, activated neutrophil-derived exosome mimetics/extracellular matrix hybrid hydrogel with antibacterial activity and wound healing promotion effect for diabetic wound therapy

Fig. 1

Scheme showing the study procedures. A total of four main steps were performed: (1) Lipopolysaccharide-activated polymorphonuclear neutrophils (LPS-aPMN) were passed through multilayer filtration membranes to prepare activated PMN exosome mimetics (aPMNEM); (2) Vascular endothelial growth factor wrapping into aPMNEM; (3) fabrication of VEGF–aPMNEM–ECM hybrid hydrogel; and (4) treatment of chronic diabetic wounds with VEGF–aPMNEM–ECM

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