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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Focused ultrasound-mediated blood-brain barrier opening combined with magnetic targeting cytomembrane based biomimetic microbubbles for glioblastoma therapy

Fig. 1

Characteristics of FeDOX@cellMBs. (A) TEM images of FeDOX. (B) Size distribution of FeDOX. (C) UV–vis spectra of FeDOX and its constituents. (D) Cell membranes of cerebral vascular endothelial cells were extracted and fused with lipid components to prepare biotype ultrasonic microvesicles (cellMBs). Scale bar = 1 μm. (E) SDS-PAGE protein analysis of bEnd.3 cell, cellMBs and MBs. (F) TEM images of MBs, cellMBs and FeDOX@cellMBs. (G) Zeta potential of FeDOX@cellMBs and cellMBs. (H) Size distribution and concentration of FeDOX@cellMBs. (n = 3, x ± SD. **** P < 0.0001)

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