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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Exosome-derived circ_0001785 delays atherogenesis through the ceRNA network mechanism of miR-513a-5p/TGFBR3

Fig. 5

circ_0001785 promotes the proliferation and inhibits the apoptosis, and migration via miR-513a-5p/TGFBR3 in endothelial. A Representative images of apoptosis, cell scratch, and proliferation after 24 h of transfection into endothelial cells using overexpressed circ_0001785 or circ_NC. B Analysis of cell proliferation by EdU assay. C Analysis of migration area by cell scratch assay. D Analysis of apoptosis by PI + hoechst. E qRT-PCR assay for the detection of TGFBR3 expression after 24 h of transfection into endothelial cells using overexpressed circ_0001785 or circ_NC. Results are expressed as the mean ± SEM; student’s t-test or one-way ANOVA. *P < 0.05, **P < 0.01, *** P < 0.001, **** P < 0.0001

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