Fig. 6

Establishment of an in vivo model of endothelial injury in atherosclerosis A Mice were divided into 5 groups. The tail vein of mice was treated with circRNA. B HE-stained images of atherosclerotic lesions and aortic root lesion areas C Masson stained images of paraffin sections D Immunohistochemical staining of endothelial CD31 at the aortic root lesion in mice. E HE staining of aortic root lesion area F Massonr staining of collagen area G, H HE and Masson staining of plaque tissue in patients with lower extremity atherosclerosis. Results are expressed as mean ± SEM; Student’s t test or one-way ANOVA. **P < 0.01