Fig. 8

Wound healing properties of PC, PCS, and PCS/TMP/TMPNPs in a rat model of full-thickness excisional wound. Photographs of wound closure percentage in different groups at weeks 1, 2, and 3 after implantation (A). Data indicate that the wound closure rate was faster and higher in the groups that received nanofibrous mats compared to the mat-free rats (p < 0.05). We found non-significant differences in wound closure percent between the PC, PCS, and PCS/TMP/TMPNPs at all-time points (p > 0.05). The wound closure rate and contraction ability were more prominent in the PCS and PCS/TMP/TMPNPs rats compared to the other groups (B). The data are presented as mean ± SD. One-Way ANOVA with Turkey analysis (n = 3; *p < 0.05, **p < 0.01, and ***p < 0.001)