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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Functional nanoparticle-enabled non-genetic neuromodulation

Fig. 8

a Schematic diagram showing the transduction and switch processes of magneto-mechanical signal induced by magnetic nanomaterials for modulating the fate of cells. Reprinted with permission [69]. Copyright 2018, Wiley–VCH Verlag GmbH & Co. KGaA, Weinheim. b Structure diagram describing the m-Torquer nanosystem. c The comparison of generation ability of torque force in rotating CMA of m-Torquer to Dynabead and Spherotech, which are magnetic beads in the market. d The expression of c-Fos analyzed by PCR with reverse transcription (RT-PCR) in neurons which expressed Piezo1 and were stimulated by m-Torquer with a rotating CMA. β-Actin (ACTB) is a housekeeping gene and Yoda1 were used to activate Piezo1. The movement loca of 5 mice after being treated by m-Torquer with (e) and without (f) CMA. Reprinted with permission [41]. Copyright 2021, Springer Nature

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