Fig. 3

Analytical performance of the biosensor. A Schematic illustration of the DT-LCHA strategy. B DPV responses and (C) corresponding calibration curve of target miRNA with the concentration from 100 aM to 100 pM using DT-LCHA. D Schematic illustration of the tradition CHA strategy. B DPV responses and (C) corresponding calibration curve of target miRNA with the concentration from 10 pM to 100 nM using DT-LCHA. G DPV signal and (H) DPV results of target miRNA and five interferences. I Intra-batch inter-batch variation of DT-LCHA. The error bars are the standard deviations by three repetitive assays (n = 3)