Table 3 Overview of MSNs-based delivery systems to targeted elimination of bacterial biofilm

Ligand-targeted

Lectin concanavalin A (ConA)

E. coli

MSNConA@LEVO

[155]

Lysostaphin、serrapeptase、DNase I

Methicillin-resistant S. aureus (MRSA)

Lys/Ser/DN@MSN

[158]

Electrostatic interactions

Polyethyleneimine (PEI)

S. aureus

AHMSN@GA@PEI@Cur

[160]

N-(2-aminoethyl)-3- aminopropyltrimethoxysilane (DAMO)

E. coli

MSN-DAMO@LEVO

[135]