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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Designing a microbial fermentation-functionalized alginate microsphere for targeted release of 5-ASA using nano dietary fiber carrier for inflammatory bowel disease treatment

Fig. 3

Therapeutic effects of NDF-M1 in mice. A Scheme of the treatment procedures. B and C Changes in body weight and DAI during 30 days of treatment. The scores were graded according to DAI, including rectal bleeding, loose stools and body weight. D and E Representative photos of colons and colon length statistics. The colon length was measured using Image J. F Representative H&E-stained histological sections of colonic tissues. The degree of inflammatory cell infiltration is delineated by green arrows. G The levels of oxidative mediators, including MDA, CAT, and MPO. Their production in the colonic tissue homogenates was detected by their respective assay kits. H The expression levels of representative IL-1β inflammatory cytokines in colonic tissue, which were detected by ELISA. *p < 0.05 and ***p < 0.001 versus the model group. All data are presented as the mean ± SD (n = 6)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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