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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Designing a microbial fermentation-functionalized alginate microsphere for targeted release of 5-ASA using nano dietary fiber carrier for inflammatory bowel disease treatment

Fig. 7

Quantitative analysis of the biodistribution of 5-ASA, proteins and GLCUA in vivo. A and B The production of 5-ASA in serum and colon contents from different sites. Mice with acute colitis induced by 3.0% DSS for 7 days were treated with 5-ASA or NDF-M1/H. Wild-type mice were used as controls and treated identically. Serum was collected to be used for the detection of 5-ASA by LC‒MS/MS. C The contents of CLCUA in colon contents from different sites. The IBS site and non-IBS site of mice with acute colitis were collected to detect the levels of 5-ASA, proteins and GLCUA by LC‒MS/MS, BCA Kit and polysaccharide decomposition methods, respectively. ***p < 0.001. All data are presented as the mean ± SD (n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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