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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Hypoxic mesenchymal stem cell-derived exosomes promote the survival of skin flaps after ischaemia–reperfusion injury via mTOR/ULK1/FUNDC1 pathways

Fig. 2

Flap model, Schematic diagram of surgery and experimental design. A The caudal superficial epigastric skin free flap (3 × 6 cm2). B Intraoperative Vascular Anatomy: EA epigastric artery, EV epigastric vein, FA femoral artery, FV femoral vein, 1 (ligatures of lateral circumflex FA and FV), 2 (ligatures of saphenous artery and vein), 3 (ligatures of proximal caudal FA and FV). C Anastomose the femoral artery and femoral vein with 10–0 nylon suture. D Experimental process design. E In vivo tracking of DiR-labeled exosomes

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