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Fig. 9 | Journal of Nanobiotechnology

Fig. 9

From: Hypoxic mesenchymal stem cell-derived exosomes promote the survival of skin flaps after ischaemia–reperfusion injury via mTOR/ULK1/FUNDC1 pathways

Fig. 9

Antagomir-421-3p abolishes the therapeutic effect of Hypo-Exo. A Representative skin flap appearance of each group on the7th day after operation. B The flap survival rate of each group on the 7th day after operation (*P < 0.05, **P < 0.01). C Representative histology images (Original magnification 40X, bar size 20 μm). D CD31 immunohistochemical detection in each group (Original magnification 40X, bar size 20 μm). E Double immunofluorescence staining of mTOR(red) and DAPI (bule) in each group (bar size 50 μm). F Quantitative data of CD31 positive blood vessels in each group (***P < 0.001, ****P < 0.0001). G Statistical evaluation of Mean fluorescence intensities in each group (*P < 0.05). Bars indicated means ± SD

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Journal of Nanobiotechnology

ISSN: 1477-3155

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