Fig. 5From: Targeted co-delivery of curcumin and erlotinib by MoS2 nanosheets for the combination of synergetic chemotherapy and photothermal therapy of lung cancera The relative cell viability of A549 cells treated with Cur, Er, Cur + Er, and MoS2-PEG-Biotin-Cur/Er as a function of Cur or Er concentration. Significant differences between the MoS2-PEG-Biotin-Cur/Er group and the other groups are indicated as *p < 0.05 and **p < 0.01. b The relative cell viability of A549 cells after various treatments. The cells were treated with Cur, Er, Cur + Er, MoS2-PEG-Biotin, and MoS2-PEG-Biotin-Cur/Er ([MoS2-PEG-Biotin] = 100 μg/mL, [Cur] = 20 μg/mL, [Er] = 10 μg/mL) for 2 h, washed with PBS, and treated with fresh cell medium. After exposure to NIR irradiation (0 or 1 W/cm.2) for 10 min, the cells were incubated for another 48 h before the MTT assay. Significant differences between the MoS2-PEG-Biotin-Cur/Er group and the other groups are indicated as *p < 0.05 and **p < 0.01. c, d Flow cytometry analysis of apoptotic A549 cells after various treatments mentioned in section “Cell apoptosis”. Significant differences between the MoS2-PEG-Biotin-Cur/Er + NIR group and other experimental groups are indicated as **p < 0.01Back to article page