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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: A novel near-infrared EGFR targeting probe for metastatic lymph node imaging in preclinical mouse models

Fig. 5

LP-S enables high contrast LNs imaging in vivo. (a) Representative NIR fluorescence images and heat maps of sciatic and popliteal LNs at different time points after local injection of LP-S or ICG (25ug/ml, 50ul). Yellow circle labeling of sciatic lymph node (sLN) and red circle labeling of popliteal lymph node (pLN). (b) Cross-sectional fluorescence intensity profiles of LP-S or ICG along the line in images after 30 min of injection. (c) Quantitative analysis of fluorescence intensity in sLNs and pLNs shown in (a) (mean ± SD, n = 3). (d) Signal to background ratio (SBR) of pLNs shown in (a) (mean ± SD, n = 3)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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