Fig. 7

LP-S enables fluorescence-guided surgery for the excision of cervical mLNs in tongue cancer mice. (a) Representative NIR fluorescence images and heat maps of cervical lymphatic drainage at different time points after local intra-tumoral injection of LP-S (25ug/ml, 50ul). (b) Fluorescence-guided surgery for the excision of cervical LNs after 24 h injection, including highlighting (red circle) and contralateral (yellow circle) LNs. (c) Fluorescence images of excised cervical LNs after 24 h injection of LP-S. H&E staining of highlighted LNs confirmed metastasis