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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Macrophage targeted iron oxide nanodecoys augment innate immunological and drug killings for more effective Mycobacterium Tuberculosis clearance

Fig. 3

Selective cellular uptake of IONPs-PAA-PEG-MAN by primary macrophages from intraepithelial lymphocytes of Mtb infected rhesus macaques. A Cellular uptake of DI@IONPs-PAA-PEG-MAN by endothelium, T cells, B cells and macrophages from the intraepithelial lymphocytes of rhesus macaqus after 3 h treatment. B Statistical analysis for cellular uptake of DI@IONPs-PAA-PEG-MAN by endothelium, T cells, B cells and macrophages from the intraepithelial lymphocytes of rhesus macaques after 3 h treatment, n = 3, ANOVA-Tukey analysis was applied for the comparative analysis of data, **p < 0.01. C Cellular uptake of DI@IONPs-PAA-PEG-MAN by endothelium, T cells, B cells and macrophages from the intraepithelial lymphocytes of rhesus macaqus after 3 h treatment. D Statistical analysis for the cellular uptake of DI@IONPs-PAA-PEG-MAN and DI@IONPs- PAA-PEG in endothelium, T cells, B cells and macrophages from the intraepithelial lymphocytes of rhesus macaqus after 3 h treatment, the positive cell percentages of DI@IONPs-PAA-PEG treated cells were set as the criteria to determine the increased cellular uptake of DI@IONPs-PAA-PEG-MAN with mannose modification, n = 3, multiple t-test analysis was applied for the comparative analysis of data, *p < 0.05

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