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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Macrophage targeted iron oxide nanodecoys augment innate immunological and drug killings for more effective Mycobacterium Tuberculosis clearance

Fig. 5

Effects of IONPs-PAA-PEG-MAN and Rif@IONPs-PAA-PEG-MAN on the polarization of M.tb-infected macrophages. A Flow cytometry analysis of CD80 positive cells and CD206 positive cells in BCG-infected THP-1 macrophages after IONPs-PAA-PEG-MAN, rifampicin and Rif@IONPs-PAA-PEG-MAN treatment, control group means BCG-infected THP-1 macrophages without drug treatment. B Flow cytometry analysis of CD80 positive cells and CD206 positive cells in H37Rv-infected THP-1 macrophages after IONPs-PAA-PEG-MAN, rifampicin and Rif@IONPs-PAA-PEG-MAN treatment, control group means H37Rv-infected THP-1 macrophages without drug treatment. Statistical analysis for the effects of IONPs-PAA-PEG-MAN, rifampicin and Rif@IONPs-PAA-PEG-MAN on the percentage of CD80 positive cells in (C) BCG-infected THP-1 macrophages and (D) H37Rv-infected THP-1 macrophages, control group means BCG or H37Rv-infected THP-1 macrophages without drug treatment, n = 3, ANOVA-Tukey analysis was applied for the comparative analysis of data, ***p < 0.001

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Journal of Nanobiotechnology

ISSN: 1477-3155

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