Fig. 1

Preparation and characterization of LDC@ZnP NPs. A Schematic illustration for preparation of LDC@ZnP NPs. B TEM image of ZnP NPs with different amounts of melanin adding. The scale bar for the upper layer was 500 nm. The scale bar for the lower layer was 100 nm. C Drug loading efficiency by ZnP NPs with different amounts of melanin adding (n = 3). D Encapsulation efficiency by ZnP NPs with different amounts of melanin adding (n = 3). E TEM image of L@ZnP-M NPs, scale bar = 100 nm. F DSC curves of LDC@ZnP NPs with different amounts of DC membrane protein insertion. G TEM images of LDC@ZnP-M NPs (a) and LDC@ZnP-MA NPs (b), scale bar = 100 nm. H Hydration particle size of L@ZnP NPs, LDC@ZnP NPs and LDC@ZnP-MA NPs (n = 3). I Zeta potential of L@ZnP NPs, LDC@ZnP NPs and LDC@ZnP-MA NPs (n = 3). J Stability of LDC@ZnP NPs in PBS and FBS (n = 3)