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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Pericyte-derived exosomal miR-210 improves mitochondrial function and inhibits lipid peroxidation in vascular endothelial cells after traumatic spinal cord injury by activating JAK1/STAT3 signaling pathway

Fig. 8

Exosomal miR-210-5p conditions JAK1 by directly targeting the 3′-UTR. A Predicted target genes of miR-210-5p. B qRT-PCR to verify the expression of target genes. C miR-210-5p regulates JAK1 by directly targeting the 3′UTR region. D Luciferase reporter assay confirmed that JAK1 is a target gene of miR-210-5p. E GO enrichment analysis of miR-210-5p target genes. F, G Western blot analysis of downstream target gene expression after miRNA overexpression and knockdown

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Journal of Nanobiotechnology

ISSN: 1477-3155

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