Fig. 5
From: Near-infrared photodynamic and photothermal co-therapy based on organic small molecular dyes
ICG-PtMGs@HGd nanoplatforms for multimodal imaging-guided synergistic phototherapy. A Scheme of the ICG-PtMGs@HGd nanoplatforms as H2O2-driven oxygenator for FL/MOST/CT/MR multimodal imaging guided enhanced PDT and PTT synergistic therapy in a solid tumor. B Real-time fluorescent images of 4T1 tumor-bearing mice at different time points after administration of ICG-PtMGs@HGd; the bottom panel shows the ex vivo images examined at 24Â h postinjection. C The MSOT and 3D orthogonal MSOT images of 4T1 tumor-bearing mice after being intravenously injected with ICG-PtMGs@HGd nanoparticles at different time points. D CT signal intensity linearly fits to the concentration of ICG-PtMGs@HGd aqueous solutions; inset: the corresponding CT images. E 3D reconstructed CT images before and 12Â h after injection of ICG-PtMGs@HGd. F T1-weighted MR images after intravenous injection with ICG-PtMGs@HGd at predesigned time points [262]