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Table 1 The OSMD-based nanoplatforms for NIR photodynamic and photothermal co-therapy

From: Near-infrared photodynamic and photothermal co-therapy based on organic small molecular dyes

Therapeutic method

Nanoplatform

Size

NIR wavelength

Application

References

PDT/PTT combination therapy

Cyanine

AuNR/ICG vesicle

238.46 nm

785 nm

PC3 cells

[125]

ICG-PEI-HAuNs

122.50 nm

880 nm

SKOV3 cells

[126]

AuNR@MSN-ICG-RLA/CS(DMA)-PEG

78.50 × 37.20 nm

808 nm

MCF-7 cells

[127]

TNYL-ICG-HAuNS

70 nm

880 nm

SKOV3 cells

[135]

FAL-ICG-HAuNS

151 nm

890 nm

CT-26 cells

[136]

Fe3O4@PDA@CaCO3/ICG

17.40 nm

700–900 nm

4T1 cells

[139]

Fe-PDAP/GOx/ICG

48.90 nm

720–786 nm

MDA-MB-231 cells

[140]

Cu9S5@mSiO2-ICG@PEG-LA

50 nm

808 nm

HepG2 cells

[141]

HA-Ti@GO/ICG

700–900 nm

4T1 cells

[142]

NGO-808

20–40 nm

808 nm

A549, Lewis tumor cells

[149]

ICG/rPAA@SWCNTs

420 nm

808 nm

Hela cells

[158]

COF@probe

808 nm

3T3 cells

[159]

COF@ICG@OVA

100 nm

650 nm, 808 nm

H22 cells

[160]

UCNPs@PDA-ICG

40 nm

808 nm

H22 cells

[161]

HA-PB/ICG

290 nm

808 nm

4T1 cells

[163]

HA-PEG-CyI

112.50 nm

808 nm

4T1 cells

[164]

M@PPI-siRNA

190.50 nm

808 nm

SCC-25, B16 cells

[165]

iRGD-rHDL/ICG

86.70 nm

780–800 nm

4T1 cells

[167]

Porpyrin

P-4

46 nm

714 nm

Hela cells

[170]

AuNR@SiO2-TCPP

190 nm

660 nm, 808 nm

A549 cells

[175]

PF6-Au

60–100 nm

400–800 nm

A549 cells

[177]

Pp4N/GNR

50 nm

660 nm, 808 nm

3T3-L1, 293 T cells

[201]

GO-C60

100–400 nm

650, 808 nm

Hela cells

[202]

VONc-COF-Por

140 nm

808 nm

MCF-7

[204]

TPAPor

80 nm

690 nm

Hela cells

[209]

PB@PCN@MEM

110–140 nm

660, 808 nm

CT26 cells

[210]

Rhodamine

PSBTBT-Ce6@Rhod

149 nm

675 nm

MCF-7 cells

[215]

Squarine

BSA-Cy7-SQ/GM

300 nm

808 nm

HepG2, HL7702 cells

[219]

BODIPY

BDPTPA

40–160 nm

808 nm

143B cells

[223]

FMAB NPs

68.10 nm

775 nm

Hela cells

[225]

MTAB NPs

155 nm

808 nm

4T1 cells

[226]

Imaging-guided phototherapy

Photoacoustic imaging

COF-366

100 nm

635 nm

4T1 cells

[238]

Fluorescence imaging

Cypate, Cy7, CyI

804 nm, 776 nm, 750 nm

HepG2 cells

[244]

AgSiO2-PpIX

125 nm

630 nm, 698 nm

[245]

AuNRs@SiO2-IR795

19.40 nm-82.50 nm

795 nm, 812 nm

U251MG, HepG2 cells

[247]

Magnetic resonance imaging

FeS2@C-ICG-PEG

200 nm

808 nm

HepG2 cells

[253]

GNRs@BPP-Gd

80 nm

808 nm

4T1 cells

[256]

Multimodal imaging

ICG-PtMGs@HGd

92.50 nm

800 nm

4T1 cells

[262]

HSA-ICG

75 nm

671 nm

4T1 cells

[263]

ICG-Ag@PANI

115.70 nm

808 nm

Hela cells

[264]

PMATIB/PEI/Au nanoshell/HA

187 nm

808 nm

MCF-7 cells

[265]

FCCP NPs

100 nm

635 nm, 980 nm

A549 cells

[271]

Synergistic chemotherapy and phototherapy

Synergistic chemo/PDT/PTT

cRGD@TAT-DINPs

51.18 nm

808 nm

MDA-MB-231, A549 cells

[300]

DOX/ICG@biotin-PEG-AuNC-PCM

109.10 nm

800 nm

MCF-7 cells

[301]

Imaging-assisted tri-modal therapy

DZSM NPs

296.90 nm

638 nm, 808 nm

4T1 cells

[275]

HMPB@PEI/ICG/DOX

310.10 nm

808 nm

4T1 cells

[298]