Table 3 List of selected chitosan-based or alginate-based marketed biomedical products (mainly hemostatic biomaterials or wound dressing)

HemCon^®

Freeze-dried chitosan acetate salt

Achieving hemostasis in emergency situations

HemCon, USA

[259]

ChitoSAM^TM100

Chitosan

Hemostatic  dressings optimized to stop bleeding fast

SAM^® Medical, USA

[260]

ChitoFlex^® PRO

Chitosan

External, temporary control of severely bleeding wounds;

Providing an external barrier against bacteria

Tricol Biomedical, Inc. USA

[261, 262]

Chitoseal^®

Chitosan dressing with cellulose coating

For major wounds with bleeding

Abbott, UK

[263]

Clo-Sur P.A.D^®

Chitosan

Non-woven topical pressure dressing to accelerate hemostasis

Scion BioMedical, USA

[264]

Celox

Chitosan

For the control of massive traumatic bleeding

Sam Medical Products

[265]

TraumaStat^®

Chitosan, mesoporous silicon and polyethylene

Both hemostatic and absorbent properties

High surface area could rapidly interact with the clotting components of blood

Ore-Medix, USA

[266]

Syvek-Patch^®

High molecular-weight chitin

Claimed to be 7-folds efficient in hemostasis than fibrin glue

Marine Polymer Technologies, Burlington

[263]

Tegasorb^®

Chitosan-based hydrocolloid dressing

Promoting wound healing;

Suitable for leg ulcers, sacral wounds, chronic wounds

3 M Healthcare, USA

[267]

Chitopack C

Cotton-like chitosan

Rebuilding subcutaneous tissues, and regenerating skin regularly

Eisai, Japan

[268]

Algicell^™

Silver Calcium Alginate

Helping to strengthen dressing when wet;

Minimized fibrous residue;

Maintaining wound moist environments

Derma Sciences, USA

[269]

Guardix-SG^®

Alginate and poloxamer

For the purpose of adhesion prevention;

Genewel, South Korea

[270]

Tromboguard^®

Sodium alginate/calcium alginate, chitosan, silver salt

Immediately stop bleeding;

Possessing antibacterial activity for preventing infection

Matopat, Poland

[271]

Pharma-Algi^®

Alginate, polyurethane,

Stop bleeding;

Absorbing the exudate;

Keeping the wound moist

Pharmaplast, Egypt

[272]

Alginate

Alginate

Strong absorption capacity;

Forming gels when connect with wound exudate;

Providing moist environment for wound healing

Winner, China

[273]

Tegaderm^™

Calcium alginate

Promoting wound healing;

3 M Healthcare, USA

[274]

Alginate wound dressing

Alginate

Efficient absorption of exudate;

Promoting wound healing;

Pain relief for patients

Shinva Ande Healthcare Apparatus, China

[273]