Table 5 List of clinical studies using MSCs combined with biomaterials for bone tissue regeneration listed in clinicaltraisl.gov
Bone defect | Cell types | Sponsor | NCT number | Phase | Patient | Scaffold |
|---|---|---|---|---|---|---|
Maxillary cyst | Mesenchymal stem cell | Red de terapia celular | NCT01389661 | 2 | 11 | BioMax (a serum cross-linked scaffold) |
Periodontal intrabony defects | Amnion membrane | Krishnadevaraya College of Dental Science | NCT02635529 | 4 | 10 | Deproteinized bovine bone mineral and collagen membrane |
Periodontal disease | Dental pulp stem cell | University of Turine | NCT03386877 | Not applicable | 29 | Collagen scaffold |
Cleft lip and palate | Dental pulp MSCs | Hospital Sirio-libanse | NCT03766217 | 3 | 6 | HA and collagen composite scaffold |
Osteochondritis | MSCs | Istituto Ortopedico Rizzoli | NCT02005861 | Not applicable | 140 | Collagen scaffold |
Cleft lip and palate | MSCs | Cairo University | NCT03563495 | Not applicable | 10 | Collagen scaffold |
Osteonecrosis jaw | MSCs | Red de terapia celular | NCT02566681 | 1 | 10 | TCP matrix and demineralized bone matrix |