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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Bioinspired nanovesicles released from injectable hydrogels facilitate diabetic wound healing by regulating macrophage polarization and endothelial cell dysfunction

Fig. 1

Preparation and characterization of itaconate-loaded bioinspired nanovesicles 4OI@iEC-M. (A) Schematic illustrations of the 4OI@iEC-M preparation. (B) TEM image of 4OI@iEC-M (scale bar: 200 nm and 100 nm). (C) The colocalization of fluorescence in cells derived from FITC (iEC membrane) and DiD (M1 membrane) dyes of iEC-M group (scale bar: 20 μm). (D) The characterization of DLS demonstrated that iEC-M and 4OI@iEC-M had similar diameters of around 200 nm (n.s.: no significance). (E) The surface zeta potential of iEC-M and 4OI@iEC-M (n.s.: no significance). (F) SDS-PAGE was conducted to compare the protein profile of iECs, M1, iEC + M1 cells, iEC-M, and 4OI@iEC-M.

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